Overview & Reviews

The base E320 is replaced with the E350 for 2006. The new model name indicates a new engine -- a 3.5-liter V6 with 268 hp, a 20-percent increase from the previous E320.

• Sleek and dignified design inside and out, pleasing blend of ride and handling, sophisticated safety features, all-wheel drive available on both sedan and wagon models.

• More expensive than competitors, confusing control layout, electronically controlled brakes lack progressive feel.

User Reviews:

Showing 131 through 140 of 167.00

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  My New E350 - 2006 Mercedes-Benz E-Class
  By Dennis K ALbers - December 17 - 3:36 am

  I traded my C320 in for this new E350, and could not be more happy. Outstanding performance and comfort is great. The new larger engine still gives great mileage also. I would recommend this vehicle to all in that market.

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  What a Lemon - 2006 Mercedes-Benz E-Class
  By Lemon Car - December 14 - 2:20 am

  Bought it 6/29. At 1000 miles, notification of airbag malfunction. Mercedes tells me not to drive it for safety. 600 miles after it got fixed, another notification of airbag malfunction. Mercedes has too many electrical problems. Never had problems with any of my Japan made cars (Lexus, Infiniti).

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  What a great car - 2006 Mercedes-Benz E-Class
  By Alex - December 12 - 5:50 pm

  I never thought I would own a Mercedes. I always felt they were and old persons car. This CDI as a lot of power. I drove from south Jersey to 20 miles from Georgia on one tank of fuel. I bet I could have made it to Georgia. I lease the car and the only way I will not buy it after the lease is if Mercedes puts that motor in its S class.

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  Love this car - 2006 Mercedes-Benz E-Class
  By srsmartin - November 24 - 7:03 am

  This cars average mileage for its first 51,000 miles is 30,6. On the highway I get 41+ at 70 mph. Add Mercedes legendary comfort and handling and this is a great car. I bought it used in 2009 from a dealer with a full MB warranty for $28 k. Ill never buy a new one again! It is my fourth Benz/first diesel, and I am now a diesel convert. Why drive anything else?

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  Best MB Diesel that I have owned - 2006 Mercedes-Benz E-Class
  By Deezil Jim - November 18 - 4:53 pm

  This car has performed exceptionally well since I purchased it from dealer. It had approx 28k at purchase. I purchased the MB extended warranty out to 5 year/100k to cover major component replacements. Best mileage was trip from El Paso,TX to destination near Fort Worth,TX (609 miles)this year, using air, with cruise control set at 70 MPH. With a few stops along the Interstate, I averaged 42.5 mpg to destination.Onboard computer at arrival said I could go another 280+ miles till refuel.(E-320 CDI has 21.0 gallontank. On board computer says that I have overall average of 33.5 mpg since purchase of car-mostly city driving mixed with some x-country trips. E- 320CDI, BEST of 4 diesel cars I owned!

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  Great car. But poor engine quality - 2006 Mercedes-Benz E-Class
  By mbzpain - October 19 - 12:43 am

  Love this car, great cruiser, comfortable, great mileage and power. BUT, Mercedes has delivered a car with a poorly designed engine. At 62K, I got check engine light and taking to the dealer was informed that I have to replace the balance shaft of my engine for a cost of close to $6K. According to the advisor and validated by the many articles you can find on the web. Mercedes, E350 engine (this affects E350, ML350 and many other C class cars using the same engine) was built using a balance shaft that was not tempered properly. This affects 10% to 15% of the cars between 2006 and 2007 Worst of all Mercedes will not stand behind the poorly manufactured engine !!!

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  At last - 2006 Mercedes-Benz E-Class
  By Tony - August 17 - 6:13 am

  I just purchased my new CDI. I had driven older diesel Mercedes so, was familiar with the car. However, I was amazed at how quiet and powerful the new engines are. In addition to the many outstanding qualities of this car, the MPG is incredible. I have gone from 2 tanks per week (Range Rover) to 1 tank per 1 1/2 weeks. What a difference. Way to go Mercedes!

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  My Mercedes - 2006 Mercedes-Benz E-Class
  By John Grace - August 16 - 12:33 pm

  The E320 CDI is a real driving pleasure, comfortable, amazing pick up and accelaration and a wonderful stable driving platform - minimum roll at cornering. A car to enjoy and keep

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  The best - 2006 Mercedes-Benz E-Class
  By xman - August 1 - 5:10 pm

  This car is amazing and it is fast for a diesel. The E class is also nice in the interior. The gas mileage is suprising for a Mercedes Benz of any kind, let alone the E class

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  Disappointing - 2006 Mercedes-Benz E-Class
  By Lonnie - July 14 - 8:53 am

  I’ve always wanted a Mercedes. To me, they were the epitome of luxury cars. Im sorry to say I have been terribly disappointed. For what I paid I expected a top of the line vehicle, but got far less than I could have gotten from a new Camry. To start with, the navigation system is very important to me, yet the E320 has no touch screen, no voice command, not even blue tooth (some Japanese economy cars have blue tooth). In fact, the processor is so slow it can’t present but a few streets at a time, and has no readable compass in the nav mode. No right arm rest for the driver if you use the cup holder. I could go on but space is limited. I wish I hadn’t given up my Camry for this car.